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Palladium/Copper Dual Catalysis for the Cross‐Coupling of Aryl(trialkyl)silanes with Aryl Bromides
Author(s) -
Komiyama Takeshi,
Minami Yasunori,
Furuya Yuki,
Hiyama Tamejiro
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201712081
Subject(s) - aryl , silanes , chemistry , palladium , organic chemistry , catalysis , polymer chemistry , silane , alkyl
Whereas aryl(trialkyl)silanes are considered to be ideal organometallic reagents for cross‐coupling reactions owing to their stability, low toxicity, solubility, and easy accessibility, they are generally inert under typical cross‐coupling conditions. Disclosed herein is a palladium/copper catalytic system that enables the cross‐coupling of trimethyl, triethyl, tert‐butyldimethyl, and triisopropyl aryl silanes with aryl bromides. This process is applicable to the sequential C−H and C−Si bond arylation of thiophenes and the synthesis of poly(thiophene–fluorene)s.