Premium
Mild Reduction of Phosphine Oxides with Phosphites To Access Phosphines
Author(s) -
Li Peng,
Wischert Raphael,
Métivier Pascal
Publication year - 2017
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201709519
Subject(s) - phosphine , reagent , phosphine oxide , chemistry , catalysis , oxide , combinatorial chemistry , phosphorus , inorganic chemistry , organic chemistry
A new method for the iodine‐catalyzed reduction of phosphine oxides with phosphites at room temperature is reported. The mild reaction conditions, scalability, and simple purification requirements render it a method of choice for the large‐scale production and facile regeneration of a variety of phosphines. Mechanistic studies, supported by DFT calculations of the oxygen transfer between the starting phosphine oxide and the phosphite reagent, are also presented. Such transmutations of phosphorus species were previously unknown.