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A Metal–Organic Framework with Exceptional Activity for C−H Bond Amination
Author(s) -
Wang Le,
Agnew Douglas W.,
Yu Xiao,
Figueroa Joshua S.,
Cohen Seth M.
Publication year - 2018
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201709420
Subject(s) - amination , catalysis , chemistry , intermolecular force , combinatorial chemistry , organic synthesis , metal , organic chemistry , molecule
The development of catalysts capable of fast, robust C−H bond amination under mild conditions is an unrealized goal despite substantial progress in the field of C−H activation in recent years. A Mn‐based metal–organic framework (CPF‐5) is described that promotes the direct amination of C−H bonds with exceptional activity. CPF‐5 is capable of functionalizing C−H bonds in an intermolecular fashion with unrivaled catalytic stability producing >10 5 turnovers.