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Nickel‐Catalyzed Intermolecular Carbosulfonylation of Alkynes via Sulfonyl Radicals
Author(s) -
GarcíaDomínguez Andrés,
Müller Simona,
Nevado Cristina
Publication year - 2017
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201704862
Subject(s) - sulfonyl , nickel , radical , chemistry , catalysis , intermolecular force , organic chemistry , polymer chemistry , combinatorial chemistry , molecule , alkyl
β,β‐Disubstituted vinyl sulfones were obtained with complete regio‐ and stereocontrol in a multicomponent reaction involving alkynes, organoboronic acids, and sulfonyl chlorides in the presence of a nickel catalyst. The reaction proceeds via sulfonyl radicals generated in situ under mild reaction conditions.