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Efficient Construction of Well‐Defined Multicompartment Porous Systems in a Modular and Chemically Orthogonal Fashion
Author(s) -
Gao Ning,
Tian Tian,
Cui Jiecheng,
Zhang Wanlin,
Yin Xianpeng,
Wang Shiqiang,
Ji Jingwei,
Li Guangtao
Publication year - 2017
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201612280
Subject(s) - modular design , flexibility (engineering) , porosity , computer science , construct (python library) , nanotechnology , distributed computing , modular construction , fabrication , microsphere , microfluidics , well defined , materials science , chemical engineering , mathematics , engineering , statistics , composite material , operating system , medicine , mathematical analysis , alternative medicine , pathology , programming language
A microfluidic assembly approach was developed for efficiently producing hydrogel spheres with reactive multidomains that can be employed as an advantageous platform to create spherical porous networks in a facile manner with well‐defined multicompartments and spatiotemporally controlled functions. This strategy allows for not only large scale fabrication of various robust hydrogel microspheres with controlled size and porosity, but also the domains embedded in hydrogel network could be introduced in a modular manner. Additionally, the number of different domains and their ratio could be widely variable on demand. More importantly, the reactive groups distributed in individual domains could be used as anchor sites to further incorporate functional units in an orthogonal fashion, leading to well‐defined multicompartment systems. The strategy provides a new and efficient route to construct well‐defined functional multicompartment systems with great flexibility and extendibility.