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A Molecular Circuit Regenerator to Implement Iterative Strand Displacement Operations
Author(s) -
DelRosso Nicole V.,
Hews Sarah,
Spector Lee,
Derr Nathan D.
Publication year - 2017
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201610890
Subject(s) - regenerative heat exchanger , limit (mathematics) , computation , computer science , reversible computing , chemistry , topology (electrical circuits) , materials science , nanotechnology , combinatorial chemistry , algorithm , physics , engineering , electrical engineering , mathematics , thermodynamics , quantum computer , quantum mechanics , mathematical analysis , heat exchanger , quantum
The predictable chemistry of Watson–Crick base‐pairing imparts a unique structural programmability to DNA, enabling the facile design of molecular reactions that perform computations. However, many of the current architectures limit devices to a single operational cycle. Herein, we introduce the design of the “regenerator”, a device based on coupled enthalpic and entropic reactions that permits the regeneration of molecular circuit components.

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