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Synthesis of Bradyrhizose Oligosaccharides Relevant to the Bradyrhizobium O‐Antigen
Author(s) -
Li Wei,
Silipo Alba,
Gersby Lotte Bettina Andersen,
Newman MariAnne,
Molinaro Antonio,
Yu Biao
Publication year - 2017
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201610680
Subject(s) - bradyrhizobium , glycosylation , innate immune system , antigen , chemistry , immune system , biochemistry , biology , immunology , receptor , rhizobium , gene
The unique α‐(1→7)‐bradyrhizoside linkages are constructed for the first time via judicious choice of the glycosylation partners and conditions, thus tetra‐ and penta‐bradyrhizosides relevant to the peculiar O‐antigen of Bradyrhizobium are synthesized, which are shown to adopt the defined right‐handed helical conformations and to be unable to induce innate immune responses in plants.