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Aryl(triethyl)silanes for Biaryl and Teraryl Synthesis by Copper(II)‐Catalyzed Cross‐Coupling Reaction
Author(s) -
Komiyama Takeshi,
Minami Yasunori,
Hiyama Tamejiro
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201608667
Subject(s) - silanes , aryl , catalysis , chemistry , silylation , reagent , copper , fluoride , organic chemistry , coupling reaction , polymer chemistry , inorganic chemistry , alkyl , silane
Aryl(triethyl)silanes are found to undergo cross‐coupling with iodoarenes in the presence of catalytic amounts of CuBr 2 and Ph‐Davephos, as well as cesium fluoride as a stoichiometric base. Because the silicon reagents are readily accessible through catalytic C−H silylation of aromatic substrates, the net transformation allows coupling of aromatic hydrocarbons with iodoarenes via triethylsilylation.