Premium
Interband Absorption Enhanced Optical Activity in Discrete Au@Ag Core–Shell Nanocuboids: Probing Extended Helical Conformation of Chemisorbed Cysteine Molecules
Author(s) -
Bao Zhi Yong,
Zhang Wei,
Zhang YongLiang,
He Jijun,
Dai Jiyan,
Yeung ChiTung,
Law GaLai,
Lei Dang Yuan
Publication year - 2017
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201607563
Subject(s) - molecule , biomolecule , absorption (acoustics) , circular dichroism , cysteine , metal , chemistry , crystallography , nanostructure , adsorption , materials science , nanotechnology , photochemistry , organic chemistry , enzyme , composite material
Detailed understanding of the interaction between a chiral molecule and a noble metal surface is essential to rationalize and advance interfacial self‐assembly of amino acids and metal‐mediated anchoring of proteins. Here we demonstrate that individual Au@Ag core–shell nanocuboids can serve as a plasmonic reporter of an extended helical network formed among chemisorbed cysteine molecules, through generating an interband absorption enhanced, Ag‐surface‐exclusive circular dichroism (CD) band in the UV region. The observed unusual, strong CD response in the hybrid Au@Ag–cysteine system can be used to probe in real time conformational evolution and structural rearrangement of biomolecules in general and also monitor the interfacial interaction between a metal surface and an adsorbed molecule, opening up the possibility of using Ag nanostructures as promising stereochemically attuned nanosensors.