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Highly Diastereo‐ and Enantioselective Cu‐Catalyzed Borylative Coupling of 1,3‐Dienes and Aldimines
Author(s) -
Jiang Liyin,
Cao Peng,
Wang Min,
Chen Bin,
Wang Bing,
Liao Jian
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201607493
Subject(s) - enantioselective synthesis , aldimine , catalysis , chemistry , coupling reaction , compatibility (geochemistry) , organic chemistry , combinatorial chemistry , materials science , composite material
A Cu‐catalyzed diastereo‐ and enantioselective borylative coupling reaction of 1,3‐dienes with imines was realized. Branched homoallylic amines are readily prepared in a syn ‐selective manner with high regio‐, diastereo‐ and enantioselectivity. Moreover, these three‐component coupling reactions feature good functional‐group compatibility and easy access to the substrates and catalyst.