Copper‐Catalyzed Vicinal Diphosphination of Styrenes: Access to 1,2‐Bis(diphenylphosphino)ethane‐Type Bidentate Ligands from Olefins | Zendy

Okugawa Yuto | Zendy; Hirano Koji | Zendy; Miura Masahiro | Zendy

Premium

Copper‐Catalyzed Vicinal Diphosphination of Styrenes: Access to 1,2‐Bis(diphenylphosphino)ethane‐Type Bidentate Ligands from Olefins

Author(s) -

Okugawa Yuto,

Hirano Koji,

Miura Masahiro

Publication year - 2016

Publication title -

angewandte chemie

Language(s) - English

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.201606976

Subject(s) - chemistry , vicinal , phosphine , denticity , copper , catalysis , trimethylsilyl , carbene , pyridine , medicinal chemistry , phosphine oxide , organic chemistry , metal

A copper/N‐heterocyclic carbene (NHC) catalyzed oxidative vicinal diphosphination of styrenes with diphenyl(trimethylsilyl)phosphine proceeds in the presence of LiO t Bu and a pyridine N ‐oxide/MnO 2 combined oxidant to deliver the corresponding 1,2‐bis(diphenylphosphino)ethanes (DPPEs) in good yields. The present copper catalysis can provide access to the DPPE‐type ligands directly from the relatively simple alkenes.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research