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Copper‐Catalyzed Vicinal Diphosphination of Styrenes: Access to 1,2‐Bis(diphenylphosphino)ethane‐Type Bidentate Ligands from Olefins
Author(s) -
Okugawa Yuto,
Hirano Koji,
Miura Masahiro
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201606976
Subject(s) - chemistry , vicinal , phosphine , denticity , copper , catalysis , trimethylsilyl , carbene , pyridine , medicinal chemistry , phosphine oxide , organic chemistry , metal
A copper/N‐heterocyclic carbene (NHC) catalyzed oxidative vicinal diphosphination of styrenes with diphenyl(trimethylsilyl)phosphine proceeds in the presence of LiO t Bu and a pyridine N ‐oxide/MnO 2 combined oxidant to deliver the corresponding 1,2‐bis(diphenylphosphino)ethanes (DPPEs) in good yields. The present copper catalysis can provide access to the DPPE‐type ligands directly from the relatively simple alkenes.