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Rhodium‐Catalyzed Regioselective Hydroxylation of Cage B−H Bonds of o ‐Carboranes with O 2 or Air
Author(s) -
Lyu Hairong,
Quan Yangjian,
Xie Zuowei
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201605880
Subject(s) - regioselectivity , rhodium , hydroxylation , chemistry , catalysis , cage , molecule , medicinal chemistry , oxygen , stereochemistry , organic chemistry , combinatorial chemistry , mathematics , combinatorics , enzyme
A rhodium‐catalyzed hydroxylation of a cage B4−H bond in o ‐carboranes with either O 2 or air as the oxygen source is described, and serves as a new methodology for the regioselective generation of a series of 4‐OH‐ o ‐carboranes in a one‐pot process. The use of either O 2 or air as both the oxidant and the oxygen source makes this protocol very environmentally friendly and practical.