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Recognition‐Mediated Hydrogel Swelling Controlled by Interaction with a Negative Thermoresponsive LCST Polymer
Author(s) -
Belal Khaled,
Stoffelbach François,
Lyskawa Joël,
Fumagalli Matthieu,
Hourdet Dominique,
Marcellan Alba,
Smet Lieselot De,
de la Rosa Victor R.,
Cooke Graeme,
Hoogenboom Richard,
Woisel Patrice
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201605630
Subject(s) - lower critical solution temperature , swelling , self healing hydrogels , thermoresponsive polymers in chromatography , polymer , chemical engineering , polymer chemistry , chemistry , materials science , composite material , organic chemistry , copolymer , high performance liquid chromatography , reversed phase chromatography , engineering
Most polymeric thermoresponsive hydrogels contract upon heating beyond the lower critical solution temperature (LCST) of the polymers used. Herein, we report a supramolecular hydrogel system that shows the opposite temperature dependence. When the non‐thermosesponsive hydrogel NaphtGel, containing dialkoxynaphthalene guest molecules, becomes complexed with the tetra cationic macrocyclic host CBPQT 4+ , swelling occurred as a result of host–guest complex formation leading to charge repulsion between the host units, as well as an osmotic contribution of chloride counter‐ions embedded in the network. The immersion of NaphtGel in a solution of poly(N‐isopropylacrylamide) with tetrathiafulvalene (TTF) end groups complexed with CBPQT 4+ induced positive thermoresponsive behaviour. The LCST‐induced dethreading of the polymer‐based pseudorotaxane upon heating led to transfer of the CBPQT 4+ host and a concomitant swelling of NaphtGel. Subsequent cooling led to reformation of the TTF‐based host–guest complexes in solution and contraction of the hydrogel.