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Diverse N ‐Heterocyclic Ring Systems via Aza‐Heck Cyclizations of N ‐(Pentafluorobenzoyloxy)sulfonamides
Author(s) -
Hazelden Ian R.,
Ma Xiaofeng,
Langer Thomas,
Bower John F.
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201605152
Subject(s) - heck reaction , ring (chemistry) , chemistry , catalysis , medicinal chemistry , palladium , combinatorial chemistry , stereochemistry , organic chemistry
Aza‐Heck cyclizations initiated by oxidative addition of Pd 0 ‐catalysts into the N−O bond of N ‐(pentafluoro‐benzoyloxy)sulfonamides are described. These studies, which encompass only the second class of aza‐Heck reaction developed to date, provide direct access to diverse N ‐heterocyclic ring systems.