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Towards a DNA Nanoprocessor: Reusable Tile‐Integrated DNA Circuits
Author(s) -
Gerasimova Yulia V.,
Kolpashchikov Dmitry M.
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201603265
Subject(s) - tile , dna , nanotechnology , nucleic acid , logic gate , computer science , dna computing , integrated circuit , chip , computer architecture , materials science , chemistry , optoelectronics , telecommunications , algorithm , biochemistry , composite material
Modern electronic microprocessors use semiconductor logic gates organized on a silicon chip to enable efficient inter‐gate communication. Here, arrays of communicating DNA logic gates integrated on a single DNA tile were designed and used to process nucleic acid inputs in a reusable format. Our results lay the foundation for the development of a DNA nanoprocessor, a small and biocompatible device capable of performing complex analyses of DNA and RNA inputs.