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Manganese(I)‐Catalyzed Substitutive C−H Allylation
Author(s) -
Liu Weiping,
Richter Sven C.,
Zhang Yujiao,
Ackermann Lutz
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201601560
Subject(s) - manganese , chemistry , catalysis , selectivity , carboxylate , scope (computer science) , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , computer science , programming language
The first manganese(I)‐catalyzed C−H allylations with ample scope were achieved by carboxylate assistance. The highly selective C−H/C−O functionalizations proved viable with densely substituted allyl carbonates, and the organometallic C−H allylation strategy set the stage for expedient late‐stage diversification with excellent levels of positional selectivity.