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Z ‐Selective (Cross‐)Dimerization of Terminal Alkynes Catalyzed by an Iron Complex
Author(s) -
RivadaWheelaghan Orestes,
Chakraborty Subrata,
Shimon Linda J. W.,
BenDavid Yehoshoa,
Milstein David
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201601382
Subject(s) - catalysis , chemistry , selectivity , terminal (telecommunication) , aryl , base (topology) , medicinal chemistry , combinatorial chemistry , alkyne , stereochemistry , organic chemistry , telecommunications , mathematical analysis , alkyl , mathematics , computer science
Efficient iron‐catalyzed homocoupling of terminal alkynes and cross‐dimerization of aryl acetylenes with trimethylsilylacetylene is reported. The complex [Fe(H)(BH 4 )( i Pr‐PNP)] ( 1 ) catalyzed the (cross‐)dimerization of alkynes at room temperature, with no need for a base or other additives, to give the corresponding dimerized products with Z selectivity in excellent yields (79–99 %).