Premium
Transfer of Two‐Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA‐Origami‐Based Nanoimprinting Lithography
Author(s) -
Zhang Yinan,
Chao Jie,
Liu Huajie,
Wang Fei,
Su Shao,
Liu Bing,
Zhang Lan,
Shi Jiye,
Wang Lihua,
Huang Wei,
Wang Lianhui,
Fan Chunhai
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201512022
Subject(s) - dna origami , dna nanotechnology , nanotechnology , lithography , nanostructure , colloidal gold , nanolithography , nanoscopic scale , materials science , oligonucleotide , chirality (physics) , nanoparticle , dna , chemistry , fabrication , physics , optoelectronics , medicine , chiral symmetry breaking , pathology , quantum mechanics , quark , nambu–jona lasinio model , biochemistry , alternative medicine
The precise functionalization of self‐assembled nanostructures with spatial and stereocontrol is a major objective of nanotechnology and holds great promise for many applications. Herein, the nanoscale addressability of DNA origami was exploited to develop a precise copy‐machine‐like platform that can transfer two‐dimensional oligonucleotide patterns onto the surface of gold nanoparticles (AuNPs) through a deliberately designed toehold‐initiated DNA displacement reaction. This strategy of DNA‐origami‐based nanoimprinting lithography (DONIL) demonstrates high precision in controlling the valence and valence angles of AuNPs. These DNA‐decorated AuNPs act as precursors in the construction of discrete AuNP clusters with desired chirality.