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Bottom‐Up Fabrication of Nanopatterned Polymers on DNA Origami by In Situ Atom‐Transfer Radical Polymerization
Author(s) -
Tokura Yu,
Jiang Yanyan,
Welle Alexander,
Stenzel Martina H.,
Krzemien Katarzyna M.,
Michaelis Jens,
Berger Rüdiger,
BarnerKowollik Christopher,
Wu Yuzhou,
Weil Tanja
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201511761
Subject(s) - dna origami , nanotechnology , atom transfer radical polymerization , materials science , polymer , nanoscopic scale , nanofluidics , biosensor , fabrication , nanostructure , polymerization , nanophotonics , surface modification , chemistry , medicine , alternative medicine , pathology , composite material
Bottom‐up strategies to fabricate patterned polymers at the nanoscale represent an emerging field in the development of advanced nanodevices, such as biosensors, nanofluidics, and nanophotonics. DNA origami techniques provide access to distinct architectures of various sizes and shapes and present manifold opportunities for functionalization at the nanoscale with the highest precision. Herein, we conduct in situ atom‐transfer radical polymerization (ATRP) on DNA origami, yielding differently nanopatterned polymers of various heights. After cross‐linking, the grafted polymeric nanostructures can even stably exist in solution without the DNA origami template. This straightforward approach allows for the fabrication of patterned polymers with low nanometer resolution, which provides access to unique DNA‐based functional hybrid materials.