Premium
Silver‐Catalyzed 7 ‐exo‐ dig Cyclization of Silylenolether‐ynesulfonamides
Author(s) -
Heinrich Clément F.,
Fabre Indira,
Miesch Laurence
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201510708
Subject(s) - dig , catalysis , chemistry , combinatorial chemistry , stereochemistry , organic chemistry , computer science , world wide web
Cyclization of silylenolether‐ynesulfonamides proceeds at ambient temperature under mild reaction conditions under silver catalysis. Bridged compounds were obtained exclusively through 7 ‐exo‐ dig reactions. The protocol is applicable to a wide range of substrates, thus leading to azabicyclic frameworks.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom