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Chromatographic NMR Spectroscopy with Hollow Silica Spheres
Author(s) -
GonzálezGarcía Tania,
Margola Tommaso,
Silvagni Adriano,
Mancin Fabrizio,
Rastrelli Federico
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201510203
Subject(s) - nuclear magnetic resonance spectroscopy , spheres , context (archaeology) , spectroscopy , analytical chemistry (journal) , pulsed field gradient , silica gel , chemistry , materials science , diffusion , chromatography , organic chemistry , molecule , thermodynamics , physics , quantum mechanics , astronomy , paleontology , biology
The use of micrometric hollow silica spheres is described as a strategy to reduce magnetic field inhomogeneities in the context of NMR chromatography. When employed as a stationary phase, hollow silica microspheres allow the use of common solution‐state NMR instruments to measure the diffusion coefficient perturbation induced by the interaction of the analytes with the silica surface.