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Efficient MoS 2 Exfoliation by Cross‐β‐Amyloid Nanotubes for Multistimuli‐Responsive and Biodegradable Aqueous Dispersions
Author(s) -
Kapil Nidhi,
Singh Ashmeet,
Singh Manish,
Das Dibyendu
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201509953
Subject(s) - exfoliation joint , peptide , aqueous solution , materials science , amyloid (mycology) , cationic polymerization , nanotechnology , nanostructure , chemistry , chemical engineering , biophysics , polymer chemistry , graphene , organic chemistry , biochemistry , inorganic chemistry , biology , engineering
Abstract Herein, we report the efficient exfoliation of MoS 2 in aqueous medium by short cationic peptide nanotubes featuring the nucleating core 17 LVFFA 21 of β‐amyloid (Aβ 1–42), a sequence associated with Alzheimer's disease. The role of morphology, length, and nature of the amyloid surface on exfoliation/dispersions of MoS 2 were investigated through specific mutations of the amyloid sequences. Notably, owing to the properties of both the constituents, self‐assembled soft nanostructures and MoS 2 , the hybrid dispersions responded reversibly to various stimuli, including temperature, pH, and light. Addition of a protease resulted in loss of the dispersions, which are otherwise stable for months at ambient conditions. The design flexibility of the peptide sequences, along with the stimuli‐responsiveness and biodegradability, can complement the applications of MoS 2 in diverse fields.