Premium
Acylsilanes in Iridium‐Catalyzed Directed Amidation Reactions and Formation of Heterocycles via Siloxycarbenes
Author(s) -
Becker Peter,
Pirwerdjan Ramona,
Bolm Carsten
Publication year - 2015
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201508501
Subject(s) - iridium , catalysis , chemistry , alkylation , combinatorial chemistry , organic chemistry
Exposing ortho‐amido aroylsilanes to visible light or heat leads to cyclization reactions that provide N‐heterocyclic compounds via siloxycarbenes as key intermediates. The previously unreported starting materials have been prepared by directed amidations of aromatic acylsilanes in the presence of an iridium catalyst followed by N‐alkylation.