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α‐Arylation/Heteroarylation of Chiral α‐Aminomethyltrifluoroborates by Synergistic Iridium Photoredox/Nickel Cross‐Coupling Catalysis
Author(s) -
El Khatib Mirna,
Serafim Ricardo Augusto Massarico,
Molander Gary A.
Publication year - 2016
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201506147
Subject(s) - iridium , enantiopure drug , photoredox catalysis , nickel , chemistry , catalysis , benzylamine , enantioselective synthesis , combinatorial chemistry , rhodium , photocatalysis , organic chemistry
Direct access to complex, enantiopure benzylamine architectures using a synergistic iridium photoredox/nickel cross‐coupling dual catalysis strategy has been developed. New C(sp 3 )C(sp 2 ) bonds are forged starting from abundant and inexpensive natural amino acids.