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Decarboxylative Alkynylation and Carbonylative Alkynylation of Carboxylic Acids Enabled by Visible‐Light Photoredox Catalysis
Author(s) -
Zhou QuanQuan,
Guo Wei,
Ding Wei,
Wu Xiong,
Chen Xi,
Lu LiangQiu,
Xiao WenJing
Publication year - 2015
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201504559
Subject(s) - alkynylation , photocatalysis , decarboxylation , chemistry , catalysis , visible spectrum , carbonylation , carbon monoxide , photochemistry , substrate (aquarium) , photoredox catalysis , carboxylation , combinatorial chemistry , organic chemistry , materials science , oceanography , optoelectronics , geology
Visible‐light‐induced photocatalytic decarboxylative alkynylations of carboxylic acids have been developed for the first time. The reaction features extremely mild conditions, broad substrate scope, and avoids additional oxidants. Importantly, a decarboxylative carbonylative alkynylation has also been carried out in the presence of carbon monoxide (CO) under photocatalytic conditions, which affords valuable ynones in high yields at room temperature.