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Palladium‐Catalyzed Asymmetric Reductive Heck Reaction of Aryl Halides
Author(s) -
Yue Guizhou,
Lei Kaining,
Hirao Hajime,
Zhou Jianrong Steve
Publication year - 2015
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201501712
Subject(s) - chemistry , halide , aryl halide , aryl , stereoselectivity , palladium , catalysis , dissociation (chemistry) , heck reaction , cationic polymerization , solvent , reductive elimination , organic chemistry , combinatorial chemistry , medicinal chemistry , alkyl
Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen‐bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways.