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Carbon Dioxide Reduction to Methylamines under Metal‐Free Conditions
Author(s) -
Blondiaux Enguerrand,
Pouessel Jacky,
Cantat Thibault
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201407357
Subject(s) - methylamines , chemoselectivity , chemistry , catalysis , carbon dioxide , metal , methylation , primary (astronomy) , organocatalysis , surface modification , organic chemistry , combinatorial chemistry , enantioselective synthesis , biochemistry , physics , astronomy , gene
The first metal‐free catalysts are reported for the methylation of amines with carbon dioxide. Proazaphosphatrane superbases prove to be highly active catalysts in the reductive functionalization of CO 2 , in the presence of hydroboranes. The new methodology enables the methylation of NH bonds in a wide variety of amines, including secondary amines, with increased chemoselectivity.