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Direct Catalytic Olefination of Alcohols with Sulfones
Author(s) -
Srimani Dipankar,
Leitus Gregory,
BenDavid Yehoshoa,
Milstein David
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201407281
Subject(s) - sulfone , ruthenium , catalysis , chemistry , alcohol , organic chemistry , pincer movement , allyl alcohol , combinatorial chemistry
The synthesis of terminal, as well as internal, olefins was achieved by the one‐step olefination of alcohols with sulfones catalyzed by a ruthenium pincer complex. Furthermore, performing the reaction with dimethyl sulfone under mild hydrogen pressure provides a direct route for the replacement of alcohol hydroxy groups by methyl groups in one step.