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Development of Coated Blade Spray Ionization Mass Spectrometry for the Quantitation of Target Analytes Present in Complex Matrices
Author(s) -
GómezRíos German Augusto,
Pawliszyn Janusz
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201407057
Subject(s) - mass spectrometry , analyte , chromatography , chemistry , extraction (chemistry) , sample preparation , analytical chemistry (journal) , desorption electrospray ionization , ionization , desorption , solid phase microextraction , gas chromatography–mass spectrometry , chemical ionization , ion , adsorption , organic chemistry
Coated blade spray (CBS) is a technology based on solid‐phase microextraction (SPME) that has been designed for the quick extraction/cleanup of analytes from complex matrices and direct desorption/ionization under ambient mass spectrometry conditions. The entire analytical process can be completed in less than 3 min and enables limits of quantitation in the low picogram‐per‐milliliter region to be reached.