Chemoselective Boronic Ester Synthesis by Controlled Speciation | Zendy

Fyfe James W. B. | Zendy; Seath Ciaran P. | Zendy; Watson Allan J. B. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Chemoselective Boronic Ester Synthesis by Controlled Speciation

Author(s) -

Fyfe James W. B.,

Seath Ciaran P.,

Watson Allan J. B.

Publication year - 2014

Publication title -

angewandte chemie

Language(s) - English

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.201406714

Subject(s) - pinacol , boronic acid , chemistry , aryl , palladium , suzuki reaction , combinatorial chemistry , catalysis , organic chemistry , alkyl

Control of boronic acid solution speciation is presented as a new strategy for the chemoselective synthesis of boronic esters. Manipulation of the solution equilibria within a cross‐coupling milieu enables the formal homologation of aryl and alkenyl boronic acid pinacol esters. The generation of a new, reactive boronic ester in the presence of an active palladium catalyst also facilitates streamlined iterative catalytic CC bond formation and provides a method for the controlled oligomerization of sp 2 ‐hybridized boronic esters.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research