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Lab‐on‐a‐Chip Reactor Imaging with Unprecedented Chemical Resolution by Hadamard‐Encoded Remote Detection NMR
Author(s) -
Telkki VilleVeikko,
Zhivonitko Vladimir V.,
Selent Anne,
Scotti Gianmario,
Leppäniemi Jarmo,
Franssila Sami,
Koptyug Igor V.
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201405681
Subject(s) - hadamard transform , microfluidics , nuclear magnetic resonance spectroscopy , image resolution , chemistry , two dimensional nuclear magnetic resonance spectroscopy , resolution (logic) , spectroscopy , chip , nanotechnology , materials science , computer science , physics , optics , stereochemistry , quantum mechanics , telecommunications , artificial intelligence
The development of microfluidic processes requires information‐rich detection methods. Here we introduce the concept of remote detection exchange NMR spectroscopy (RD‐EXSY), and show that, along with indirect spatial information extracted from time‐of‐flight data, it provides unique information about the active regions, reaction pathways, and intermediate products in a lab‐on‐a‐chip reactor. Furthermore, we demonstrate that direct spatial resolution can be added to RD‐EXSY efficiently by applying the principles of Hadamard spectroscopy.