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A Supramolecular Sorting Hat: Stereocontrol in Metal–Ligand Self‐Assembly by Complementary Hydrogen Bonding
Author(s) -
Young Michael C.,
Holloway Lauren R.,
Johnson Amber M.,
Hooley Richard J.
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201405242
Subject(s) - hydrogen bond , supramolecular chemistry , ligand (biochemistry) , chemistry , self assembly , metal , crystallography , counterion , stereochemistry , combinatorial chemistry , molecule , crystal structure , organic chemistry , ion , receptor , biochemistry
A combination of self‐complementary hydrogen bonding and metal–ligand interactions allows stereocontrol in the self‐assembly of prochiral ligand scaffolds. A unique, non‐tetrahedral M 4 L 6 structure is observed upon multicomponent self‐assembly of 2,7‐diaminofluorenol with 2‐formylpyridine and Fe(ClO 4 ) 2 . The stereochemical outcome of the assembly is controlled by self‐complementary hydrogen bonding between both individual ligands and a suitably sized counterion as template. This hydrogen‐bonding‐mediated stereoselective metal–ligand assembly allows the controlled formation of nonsymmetric discrete cage structures from previously unexploited ligand scaffolds.