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Copper‐Catalyzed Borylative Allyl–Allyl Coupling Reaction
Author(s) -
Semba Kazuhiko,
Bessho Naoto,
Fujihara Tetsuaki,
Terao Jun,
Tsuji Yasushi
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201404173
Subject(s) - regioselectivity , chemistry , catalysis , diene , carbene , ligand (biochemistry) , copper , selectivity , medicinal chemistry , organic chemistry , biochemistry , natural rubber , receptor
Borylative allyl–allyl coupling using allenes, bis(pinacolato)diboron, and allyl phosphates has been developed in the presence of a copper catalyst bearing an N‐heterocyclic carbene ligand. The reaction affords boryl‐substituted 1,5‐diene derivatives in good to high yields with high regioselectivity and Z selectivity.
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