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Deactivation of Cationic Cu I and Au I Catalysts for A 3 Coupling by CH 2 Cl 2 : Mechanistic Implications of the Formation of Neutral Cu I and Au I Chlorides
Author(s) -
Grirrane Abdessamad,
Álvarez Eleuterio,
García Hermenegildo,
Corma Avelino
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201403973
Subject(s) - cationic polymerization , catalysis , chemistry , chloride , copper , reagent , solvent , inorganic chemistry , crystallography , polymer chemistry , organic chemistry
Care should be exercised when using CH 2 Cl 2 as a solvent for reactions in which amines are a reagent, since undesirable deactivation of cationic copper(I) and gold(I) catalysts to form the corresponding inactive neutral chloride complexes [LMCl] (M=Cu or Au) can occur as a result of the generation of hydrogen chloride in the medium. Cu I and Au I deactivation has been proved for the Mannich three‐component coupling reaction. A series of Cu I and Au I complexes with potential mechanistic implications were isolated and characterized by X‐ray crystallography.