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Transient Substrate‐Induced Catalyst Formation in a Dynamic Molecular Network
Author(s) -
FanloVirgós Hugo,
Alba AndreaNekane R.,
Hamieh Saleh,
ColombDelsuc Mathieu,
Otto Sijbren
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201403480
Subject(s) - catalysis , substrate (aquarium) , chemistry , synthetic biology , nanotechnology , materials science , combinatorial chemistry , chemical engineering , biology , organic chemistry , computational biology , engineering , ecology
In biology enzyme concentrations are continuously regulated, yet for synthetic catalytic systems such regulatory mechanisms are underdeveloped. We now report how a substrate of a chemical reaction induces the formation of its own catalyst from a dynamic molecular network. After complete conversion of the substrate, the network disassembles the catalyst. These results open up new opportunities for controlling catalysis in synthetic chemical systems.

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