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Iridium‐Catalyzed Enantioselective CH Alkylation of Ferrocenes with Alkenes Using Chiral Diene Ligands
Author(s) -
Shibata Takanori,
Shizuno Tsubasa
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201402518
Subject(s) - enantioselective synthesis , diene , alkylation , chemistry , cationic polymerization , regioselectivity , iridium , moiety , ferrocene , catalysis , ligand (biochemistry) , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , receptor , biochemistry , natural rubber , electrode , electrochemistry
The first catalytic and enantioselective CH alkylation of ferrocene derivatives with various alkenes was achieved. A cationic iridium complex, having a chiral diene ligand, and an isoquinolyl moiety as a directing group are essential for regioselective and enantioselective CH bond activation.