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Total Syntheses of Secalonic Acids A and D
Author(s) -
Qin Tian,
Porco John A.
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201311260
Subject(s) - chemistry , stannane , kinetic resolution , monomer , total synthesis , stereochemistry , catalysis , aryl , combinatorial chemistry , organic chemistry , enantioselective synthesis , polymer , alkyl
Total syntheses of the dimeric tetrahydroxanthone natural products secalonic acids A and D are described. Key steps involve kinetic resolution of the tetrahydroxanthone core structure using homobenzotetramisole catalysis and late‐stage copper(I)‐mediated homodimerization of complex aryl stannane monomers.