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Radical Cyclization/ ipso ‐1,4‐Aryl Migration Cascade: Asymmetric Synthesis of 3,3‐Difluoro‐2‐propanoylbicyclo[3.3.0]octanes
Author(s) -
Thaharn Watcharaporn,
Soorukram Darunee,
Kuhakarn Chutima,
Tuchinda Patoomratana,
Reutrakul Vichai,
Pohmakotr Manat
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201310747
Subject(s) - cascade , intramolecular force , chemistry , aryl , radical cyclization , combinatorial chemistry , radical , stereochemistry , organic chemistry , chromatography , alkyl
A novel method for the asymmetric synthesis of 3,3‐difluoro‐2‐propanoylbicyclo‐[3.3.0]octanes involves an unprecedented intramolecular radical cyclization/ ipso ‐1,4‐aryl migration cascade.