Premium
Aerobic Oxidation in Nanomicelles of Aryl Alkynes, in Water at Room Temperature
Author(s) -
Handa Sachin,
Fennewald James C.,
Lipshutz Bruce H.
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201310634
Subject(s) - aryl , molecular oxygen , environmentally friendly , chemistry , peroxide , solubility , hydrocarbon , oxygen , metal , organic chemistry , photochemistry , combinatorial chemistry , alkyl , ecology , biology
On the basis of the far higher solubility of oxygen gas inside the hydrocarbon core of nanomicelles, metal and peroxide free aerobic oxidation of aryl alkynes to β‐ketosulfones has been achieved in water at room temperature. Many examples are offered that illustrate broad functional group tolerance. The overall process is environmentally friendly, documented by the associated low E Factors.