Bio‐Inspired Dimerization Reaction of Tryptophan Derivatives in Aqueous Acidic Media: Three‐Step Syntheses of (+)‐WIN 64821, (−)‐Ditryptophenaline, and (+)‐Naseseazine B | Zendy

Tadano Shinji | Zendy; Mukaeda Yuri | Zendy; Ishikawa Hayato | Zendy

Premium

Bio‐Inspired Dimerization Reaction of Tryptophan Derivatives in Aqueous Acidic Media: Three‐Step Syntheses of (+)‐WIN 64821, (−)‐Ditryptophenaline, and (+)‐Naseseazine B

Author(s) -

Tadano Shinji,

Mukaeda Yuri,

Ishikawa Hayato

Publication year - 2013

Publication title -

angewandte chemie

Language(s) - German

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.201303143

Subject(s) - chemistry , aqueous medium , tryptophan , combinatorial chemistry , aqueous solution , medicinal chemistry , organic chemistry , amino acid , biochemistry

Gedoppelt : Die direkte bioinspirierte Dimerisierung kommerziell erhältlicher aminfreier Tryptophanderivate in saurem wässrigem Medium liefert C 2 ‐symmetrische und nichtsymmetrische dimere Verbindungen. Weitere Reaktionen schließen knappe Synthesen natürlich vorkommender dimerer Diketopiperazinalkaloide wie (+)‐WIN 64821 (siehe Bild) in Gesamtausbeuten bis 20 % ab.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research