Nanoparticles for Drug Delivery Prepared from Amphiphilic PLGA Zwitterionic Block Copolymers with Sharp Contrast in Polarity between Two Blocks | Zendy

Cao Zhiqiang | Zendy; Yu Qiuming | Zendy; Xue Hong | Zendy; Cheng Gang | Zendy; Jiang Shaoyi | Zendy

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Nanoparticles for Drug Delivery Prepared from Amphiphilic PLGA Zwitterionic Block Copolymers with Sharp Contrast in Polarity between Two Blocks

Author(s) -

Cao Zhiqiang,

Yu Qiuming,

Xue Hong,

Cheng Gang,

Jiang Shaoyi

Publication year - 2010

Publication title -

angewandte chemie

Language(s) - German

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.200907079

Subject(s) - copolymer , nanoparticle , amphiphile , plga , chemistry , polymer chemistry , nanotechnology , polymer science , combinatorial chemistry , computer science , materials science , organic chemistry , polymer

Blockcopolymere aus Poly(carboxybetain) (PCB) und Poly(milchsäure‐co‐glycolsäure) (PLGA) mit t Bu‐Gruppen als Teil der PCB‐Monomere bilden außergewöhnlich stabile PLGA‐Kern/PCB‐Schale‐Nanopartikel, die aufgrund der COO − ‐Gruppen in der PCB‐Schale ein hohes Funktionalisierungspotenzial aufweisen (siehe Bild; EDC=1‐Ethyl‐3‐(3‐dimethylaminopropyl)carbodiimid, NHS= N ‐Hydroxysuccinimid).

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