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Stereoselective Synthesis of cis ‐β‐Methyl‐ and Phenyl‐Substituted Alkenylboronates by Platinum‐Catalyzed Dehydrogenative Borylation
Author(s) -
Ohmura Toshimichi,
Takasaki Yuta,
Furukawa Hideki,
Suginome Michinori
Publication year - 2009
Publication title -
angewandte chemie
Language(s) - German
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.200805406
Subject(s) - borylation , chemistry , catalysis , platinum , stereoselectivity , organoboron compounds , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , aryl , alkyl
Die Plätze getauscht : In Gegenwart eines Platin‐Phosphan‐Katalysators findet ein intramolekularer B(pin)/H‐Austausch statt (siehe Schema; B(pin)=4,4,5,5‐Tetramethyl‐1,3,2‐dioxaborolan‐2‐yl). Dabei bilden sich stereoselektiv cis ‐β‐Methyl‐substituierte Alkenylboronate, die nützliche Synthesebausteine sind.

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