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Organocatalytic Asymmetric Formal [3+2] Cycloaddition Reaction of Isocyanoesters to Nitroolefins Leading to Highly Optically Active Dihydropyrroles
Author(s) -
Guo Chang,
Xue MengXia,
Zhu MingKui,
Gong LiuZhu
Publication year - 2008
Publication title -
angewandte chemie
Language(s) - German
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.200800003
Subject(s) - optically active , enantioselective synthesis , formal synthesis , cinchona , chemistry , schema (genetic algorithms) , cycloaddition , organocatalysis , stereochemistry , organic chemistry , computer science , catalysis , information retrieval
Genaue Vorgaben für den Ringschluss : Asymmetrische formale [3+2]‐Cycloadditionen von α‐substituierten Isocyanestern und Nitroolefinen werden durch Cinchona‐Alkaloide katalysiert und liefern 2,3‐Dihydropyrrole mit hohen Diastereo‐ und Enantioselektivitäten (siehe Schema).

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