De Novo Design and Synthesis of Helix–Turn–Helix Structure from Short and Robust Mixed Helices Derived from C‐Linked Carbo‐β‐Amino Acids | Zendy

Sharma Gangavaram V. M. | Zendy; Subash Velaparthi | Zendy; Narsimulu Kongari | Zendy; Sankar Ampapathi Ravi | Zendy; Kunwar Ajit C. | Zendy

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De Novo Design and Synthesis of Helix–Turn–Helix Structure from Short and Robust Mixed Helices Derived from C‐Linked Carbo‐β‐Amino Acids

Author(s) -

Sharma Gangavaram V. M.,

Subash Velaparthi,

Narsimulu Kongari,

Sankar Ampapathi Ravi,

Kunwar Ajit C.

Publication year - 2006

Publication title -

angewandte chemie

Language(s) - German

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.200603084

Subject(s) - helix (gastropod) , triple helix , chemistry , stereochemistry , turn (biochemistry) , helix turn helix , crystallography , biochemistry , biology , dna binding protein , ecology , snail , gene , transcription factor

Abgeknickt : Durch Anbringen von kurzen Peptiden mit robusten gemischten 10/12‐Helices aus C‐verknüpften Carbo‐β‐aminosäuren an die schleifeninduzierende Gruppe β‐hGly‐ D ‐Pro‐Gly‐β‐hGly gelang das De‐novo‐Design eines Helix‐Schleife‐Helix‐Motivs in der Foldamerdomäne.

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