Synthesis of 1,8‐Naphthyridine C‐Nucleosides and Their Base‐Pairing Properties in Oligodeoxynucleotides: Thermally Stable Naphthyridine:Imidazopyridopyrimidine Base‐Pairing Motifs | Zendy

Hikishima Sadao | Zendy; Minakawa Noriaki | Zendy; Kuramoto Kazuyuki | Zendy; Fujisawa Yuki | Zendy; Ogawa Maki | Zendy; Matsuda Akira | Zendy

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Synthesis of 1,8‐Naphthyridine C‐Nucleosides and Their Base‐Pairing Properties in Oligodeoxynucleotides: Thermally Stable Naphthyridine:Imidazopyridopyrimidine Base‐Pairing Motifs

Author(s) -

Hikishima Sadao,

Minakawa Noriaki,

Kuramoto Kazuyuki,

Fujisawa Yuki,

Ogawa Maki,

Matsuda Akira

Publication year - 2005

Publication title -

angewandte chemie

Language(s) - German

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.200461857

Subject(s) - pairing , chemistry , base (topology) , nucleoside , base pair , combinatorial chemistry , computer science , stereochemistry , physics , mathematics , superconductivity , biochemistry , condensed matter physics , mathematical analysis , dna

Alt raus, Neu rein : Heck‐Kupplungen machten die neuartigen 1,8‐Naphthyridin‐C‐Nucleoside Na‐N O und Na‐O N (siehe Formeln) zugänglich. Oligodesoxynucleotide, die die Na‐N O ‐ und Na‐O N ‐Nucleoside enthielten, bildeten mithilfe der Basenpaarungsmotive Na‐N O :Im‐O N und Na‐O N :Im‐N O äußerst stabile Duplexe.

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