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Preparation and Synthetic Applications of 2‐Halotryptophan Methyl Esters: Synthesis of Spirotryprostatin B
Author(s) -
Miyake Fumiko Y.,
Yakushijin Kenichi,
Horne David A.
Publication year - 2004
Publication title -
angewandte chemie
Language(s) - German
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.200460419
Subject(s) - schema (genetic algorithms) , chemistry , rasch model , content (measure theory) , computer science , stereochemistry , information retrieval , psychology , mathematics , mathematical analysis , developmental psychology
Spirocyclisierung von N ‐Acyliminium‐Ionen : 2‐Halogentryptophanester sind wertvolle Synthesebausteine für die stereokontrollierte Synthese von Spiro[pyrrolidin‐3,3′‐oxindolen] (siehe Schema). Der Zellzyklus‐Inhibitor Spirotryprostatin B ist mit der hier beschriebenen Methode rasch zugänglich.

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