A Droplet‐Based, Composite PDMS/Glass Capillary Microfluidic System for Evaluating Protein Crystallization Conditions by Microbatch and Vapor‐Diffusion Methods with On‐Chip X‐Ray Diffraction | Zendy

Zheng Bo | Zendy; Tice Joshua D. | Zendy; Roach L. Spencer | Zendy; Ismagilov Rustem F. | Zendy

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A Droplet‐Based, Composite PDMS/Glass Capillary Microfluidic System for Evaluating Protein Crystallization Conditions by Microbatch and Vapor‐Diffusion Methods with On‐Chip X‐Ray Diffraction

Author(s) -

Zheng Bo,

Tice Joshua D.,

Roach L. Spencer,

Ismagilov Rustem F.

Publication year - 2004

Publication title -

angewandte chemie

Language(s) - German

Resource type - Journals

eISSN - 1521-3757

pISSN - 0044-8249

DOI - 10.1002/ange.200453974

Subject(s) - crystallization , materials science , diffusion , microfluidics , composite number , diffraction , nanotechnology , computer science , chemical engineering , physics , thermodynamics , optics , composite material , engineering

Aus einem Tröpfchen : Proteine können mit Mikrobatch‐ und Dampfdiffusionstechniken in PDMS/Glas‐Kompositbauteilen aus Volumina von wenigen Nanolitern kristallisiert werden (PDMS=Polydimethylsiloxan). Die Qualität der Kristalle kann direkt mithilfe von On‐Chip‐Röntgenbeugung beurteilt werden (siehe Bild).

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