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Formal [3+2] Addition of Acceptor‐Substituted Cyclopropylmethylsilanes with Aryl Acetylenes
Author(s) -
Yadav Veejendra K.,
Sriramurthy Vardhineedi
Publication year - 2004
Publication title -
angewandte chemie
Language(s) - German
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.200453823
Subject(s) - cyclopropane , chemistry , aryl , regioselectivity , stereochemistry , medicinal chemistry , ring (chemistry) , catalysis , organic chemistry , alkyl
Push‐pull‐Substitution macht Cyclopropane zu Syntheseäquivalenten für die 1,3‐dipolaren Synthone 2 , die formale [3+2]‐Additionen mit Arylacetylenen eingehen. Die tert ‐Butyldiphenylsilylmethyl‐substituierten Cyclopropylketone 1 reagieren in Gegenwart von TiCl 4 mit Arylacetylenen regio‐ und stereoselektiv zu den Cyclopenten‐Derivaten 3 (R= n Bu, t Bu, Ph).
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