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Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline‐2‐methanol to 2,2,3‐Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin
Author(s) -
Ori Mayuko,
Toda Narihiro,
Takami Kazuko,
Tago Keiko,
Kogen Hiroshi
Publication year - 2003
Publication title -
angewandte chemie
Language(s) - German
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.200351069
Subject(s) - stereocenter , chemistry , indoline , stereospecificity , total synthesis , stereochemistry , organic chemistry , enantioselective synthesis , catalysis
Aufbau tertiärer und quartärer Stereozentren : Eine PPh 3 /CCl 4 ‐vermittelte, stereospezifische Umlagerung von α,α‐disubstituierten Hydroxymethylindolinen zu 2,2,3‐trisubstituierten chiralen Tetrahydrochinolinen (siehe Schema) wurde für die erste Totalsynthese von Virantmycin genutzt.

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