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Allgemeine Methode zur Synthese von 2‐Azetidinonen und 2‐Azetidinylidenammoniumsalzen
Author(s) -
De Poortere Michel,
MarchandBrynaert Jacqueline,
Ghosez Léon
Publication year - 1974
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.19740860707
Subject(s) - chemistry , philosophy
RR1C:CClNMe2 (R = R1 = Me or R = Me3C, R1 = H) reacted probably as RR1C:C:N+Me2 Cl- with R2R3C:NR4 (R2 = Ph or PhCH2S; R3 = H or Ph; R4 = Me, Ph, or Me3C)in CH2Cl2 at room temp. to give 47-80% ammonium salts I (Z = N+Me2 Cl-), which on NaOH treatment gave 42-82% azetidinones I (Z = O). I were also obtained starting from RR1CHCONMe2